Hazard Trait-Based Lists

Proposition 65 (Prop 65)
Chemicals known to cause cancer and/or reproductive toxicity that are listed under Health and Safety Code section 25249.8 of the California Safe Drinking Water and Toxic Enforcement Act of 1986 (22 CCR 69502.2(a)(1)(A)).

European Community Annex VI Respiratory Sensitizers Category 1 (EC Annex VI Resp. Sens.)
Chemicals classified by the European Union as respiratory sensitizers Category 1 in Annex VI to Regulation (EC) 1272/2008 (22 CCR 69502.2(a)(1)(I)).

European Community Annex VI Carcinogens, Mutagens, and Reproductive Toxicants (EC Annex VI CMRs)
Chemicals classified by the European Union as carcinogens, mutagens, and/or reproductive toxicants Category 1A and 1B in Annex VI to Regulation (EC) 1272/2008 (22 CCR 69502.2(a)(1)(B)).

European Community Persistent, Bioaccumulative, and Toxic Substances (EC PBTs)
Chemicals included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907/2006 on the basis of Article 57(d), Article 57(e), or Article 57(f) for persistent, bioaccumulative and toxic, or very persistent and very bioaccumulative properties (22 CCR 69502.2(a)(1)(G)).

European Community Endocrine Disruptors (EC EDs)
Chemicals included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907/2006 on the basis of Article 57(f) for endocrine disrupting properties (22 CCR 69502.2(a)(1)(C)).

Integrated Risk Information System (IRIS) Neurotoxicants
Chemicals for which a reference dose or reference concentration has been developed based on neurotoxicity in the United States Environmental Protection Agency’s Integrated Risk Information System (22 CCR 69502.2(a)(1)(D)).

Integrated Risk Information System (IRIS) Carcinogens
Chemicals that are identified as “carcinogenic to humans,” “likely to be carcinogenic to humans,” or Group A, B1, or B2 carcinogens in the United States Environmental Protection Agency’s Integrated Risk Information System (22 CCR 69502.2(a)(1)(E)).

Canada Persistent, Bioaccumulative, and Inherently Toxic to the Environment (PBiT)
Chemicals that are identified as Persistent, Bioaccumulative, and Inherently Toxic to the environment by the Canadian Environmental Protection Act Environmental Registry Domestic Substances List (22 CCR 69502.2(a)(1)(H)).

International Agency for Research on Cancer (IARC) Carcinogens
Groups 1, 2A, and 2B carcinogens identified by the International Agency for Research on Cancer (22 CCR 69502.2(a)(1)(J)).

Agency for Toxic Substances and Disease Registry (ATSDR) Neurotoxicants
Neurotoxicants that are identified in the Agency for Toxic Substances and Disease Registry’s Toxic Substances Portal, Health Effects of Toxic Substances and Carcinogens, Nervous System (22 CCR 69502.2(a)(1)(K)).

U.S. EPA National Waste Minimization Program PBTs (U.S. EPA NWMP PBTs)
Persistent Bioaccumulative and Toxic Priority Chemicals that are identified by the United States Environmental Protection Agency’s National Waste Minimization Program (22 CCR 69502.2(a)(1)(L)).

National Toxicology Program, Office of Health Assessment and Translation – Human Reproductive and Developmental Toxicants (NTP OHAT – Repr. or Dev. Toxicants)
Reproductive or developmental toxicants identified in Monographs on the Potential Human Reproductive and Developmental Effects, National Toxicology Program, Office of Health Assessment and Translation (22 CCR 69502.2(a)(1)(M)).

U.S. EPA Toxics Release Inventory PBTs (U.S. EPA TRI PBTs)
United States Environmental Protection Agency’s Toxics Release Inventory Persistent, Bioaccumulative and Toxic Chemicals that are subject to reporting under the Emergency Planning and Community Right-to-Know Act section 313 (22 CCR 69502.2(a)(1)(N)).

Washington (WA) PBTs
Washington Department of Ecology’s Persistent, Bioaccumulative, Toxic (PBT) Chemicals identified in the Washington Administrative Code, title 173, chapter 173-333 (22 CCR 69502.2(a)(1)(O)).

National Toxicology Program 13th Report on Carcinogens (NTP 13th RoC)
Chemicals that are identified as “known to be” or “reasonably anticipated to be” a human carcinogen in the 13th Report on Carcinogens, United States Department of Health and Human Services, Public Health Service, National Toxicology Program (22 CCR 69502.2(a)(1)(F)).